OBAGI - Tretinoin 0.025%

Prescription-Strength Retinoid for Early Signs of Ageing and Mild to Moderate Acne

Available by prescription only. Medical assessment required.

Obagi Tretinoin 0.025% Cream is a dermatologist-trusted topical retinoid formulated to treat early skin ageing, mild acne, and uneven skin tone. With a lower concentration of prescription-grade tretinoin, this gentle cream accelerates cell turnover, improves skin clarity, and minimises the appearance of fine lines — making it an ideal introduction to retinoid therapy. Its lightweight texture absorbs easily, helping restore radiance and smoothness to tired, blemish-prone skin.

Key Benefits

• Reduces Breakouts and Clears Pores
  Promotes faster cell renewal to unclog pores, prevent acne, and calm mild inflammation.
• Diminishes Early Wrinkles and Fine Lines
  Supports collagen synthesis to smooth out fine lines and improve skin elasticity.
• Evens Out Tone and Texture
  Gently fades pigmentation irregularities and rough patches for a visibly refined complexion.
• Ideal for New Retinoid Users
  A low-strength option suitable for beginners or sensitive skin types transitioning into retinoid use.

How to Apply

Apply at night to clean, dry skin. Dispense a pea-sized amount and gently spread over the face, avoiding the eyes, lips, and nasal creases. Start with 2–3 uses per week and increase frequency as tolerated. Always apply broad-spectrum SPF in the morning to protect against sun sensitivity.

Key Active Ingredient

• Tretinoin 0.025% (Retinoic Acid) — A prescription vitamin A derivative that enhances skin renewal, unclogs pores, and reduces visible signs of ageing.

Full Ingredient List

Tretinoin 0.025%, Sorbic Acid, Isopropyl Myristate, Polyoxyl 40 Stearate, Stearic Acid, BHT, Purified Water, and other stabilisers and emollients designed for optimal skin penetration and minimal irritation.

Usage Precautions

• For prescription use only. Follow guidance from your licensed healthcare provider.
• Not suitable during pregnancy or while breastfeeding unless advised by a medical professional.
• Temporary dryness, redness, or mild peeling may occur during the adjustment phase.
• Avoid excessive sun exposure and use daily sun protection while using tretinoin.
• Discontinue use and consult a doctor if irritation becomes severe or persistent.

Frequently Asked Questions

What is tretinoin and how does it work?

Tretinoin is a prescription-strength vitamin A derivative (retinoic acid) that works by accelerating skin cell turnover. This helps unclog pores, reduce acne, fade pigmentation, and stimulate collagen production — making it one of the most clinically proven anti-ageing and acne treatments available.

What is the difference between tretinoin 0.025%, 0.05%, and 0.1%?

The concentration determines potency and tolerability. 0.025% is the gentlest and is recommended for first-time retinoid users or sensitive skin. 0.05% offers a stronger effect for those who have built up tolerance. 0.1% is the most potent and is typically reserved for experienced users under close clinical supervision.

Do I need a prescription for tretinoin?

Yes — tretinoin is a prescription-only medicine in the UK. A medical assessment is required before purchase to ensure it is appropriate for your skin and health.

How do I manage the initial dryness and peeling?

Start with 2–3 applications per week and gradually increase frequency as your skin adjusts. Use a gentle, non-comedogenic moisturiser after application and always apply SPF in the morning. The adjustment phase typically lasts 2–4 weeks.

Can I use tretinoin with other actives like vitamin C or niacinamide?

Apply tretinoin at night and vitamin C in the morning to avoid potential irritation. Niacinamide can be used in the same routine and may help reduce tretinoin-related redness. Always consult your prescriber before combining actives.

Is tretinoin safe during pregnancy?

No — tretinoin is not recommended during pregnancy or breastfeeding. Please consult your doctor for safe alternatives.