OBAGI - Nu-Derm® 3 Clear (Hydroquinone)

Prescription Only — Online Medical Assessment Required

Obagi Nu-Derm Clear #3 (57g) is a prescription-strength skin brightening cream containing 4% hydroquinone. Clinically formulated to fade dark spots, melasma, and hyperpigmentation caused by sun damage, acne, and hormonal changes.

This is Step 3 in the Obagi Nu-Derm System — one of the most trusted dermatological regimens for intensive skin tone correction.

What It Treats

• Melasma and hormone-related pigmentation
• Sunspots and UV-related discolouration
• Post-inflammatory hyperpigmentation (e.g., after acne)
• Uneven skin tone, age spots, and freckles

Prescription-Only Formula

Obagi Clear #3 contains hydroquinone 4%, a powerful skin-brightening agent available only with a prescription in the UK. You'll need to complete a quick online consultation with our UK-based clinicians before purchase.

How to Use

Apply a thin layer to clean, dry skin once or twice daily — or as instructed by your prescriber. Always follow with a broad-spectrum SPF 30+ in the morning.

Note: Do not combine with other brightening or exfoliating agents unless medically approved.

Active Ingredient

• Hydroquinone 4% — A gold-standard pigment inhibitor that blocks melanin production at the source for brighter, more even skin.

Important Safety Information

• For short-term use only, under clinical supervision.
• Not suitable during pregnancy or breastfeeding.
• May cause redness, irritation, or sensitivity during early use.
• Avoid if you have eczema, rosacea, or very sensitive skin.
• Discontinue use after 4–6 months or as advised by your prescriber.

UK Delivery & Online Prescription

All hydroquinone products require a free online skin consultation before dispatch. Approved orders are sent via tracked UK delivery. We are a UK-regulated supplier — your safety is our priority.

Not sure if this is right for your skin? Speak to our team for advice on Obagi Clear vs Clear FX, or guidance on hyperpigmentation treatment.

Frequently Asked Questions

What is hydroquinone and how does it work?

Hydroquinone is a clinically proven skin-brightening agent that works by inhibiting the enzyme responsible for melanin production. At 4% concentration, it is one of the most effective treatments available for melasma, sunspots, and post-inflammatory hyperpigmentation.

Why do I need a prescription for this product?

Hydroquinone at 4% is a prescription-only medicine in the UK. Our online consultation process connects you with UK-based clinicians who will assess your suitability before approving your order.

What is the difference between Obagi Clear #3 and Clear FX?

Obagi Clear #3 contains 4% hydroquinone (prescription only), while Clear FX uses arbutin as a non-prescription alternative. Clear #3 is generally considered more potent for stubborn pigmentation. Our team can advise which is right for you.

How long does it take to see results?

Most patients begin to see visible improvements in skin tone and dark spots within 4–8 weeks of consistent use, with optimal results typically achieved over a full treatment course of 4–6 months.

Can I use this product if I am pregnant or breastfeeding?

No — Obagi Clear #3 is not suitable for use during pregnancy or breastfeeding. Please consult your doctor for alternative options.