

Target All Stages of Acne Formation, Prevent Future Breakouts and Minimise Post-Acne Marks with a Clinically Proven Potent Blemish Complex
ZO Skin Health® Retinol + Blemish Complex is a clinically proven topical treatment formulated to combat acne and restore skin clarity. Combining maximum-strength 1% microemulsion retinol with 2% encapsulated salicylic acid and tranexamic acid, it targets all stages of acne formation — from initial congestion through to active breakouts and post-inflammatory hyperpigmentation — in a single, advanced formula.
Retinol boosts collagen production, accelerates cellular turnover, and refines skin texture, while encapsulated salicylic acid penetrates deep into the pore lining to dissolve congestion and prevent future breakouts. Tranexamic acid addresses the post-acne marks and pigmentation that persist after blemishes resolve, delivering a clearer, more balanced, and visibly smoothed complexion with consistent use.
Begin use gradually — apply 2–3 times per week, both morning and evening, before SPF. Gradually increase to daily use as tolerated. Do not apply around the eye area. Always follow with a ZO Skin Health® mineral SPF 30 or higher every morning. Introduce slowly to allow the skin to adjust to the high-potency retinol and salicylic acid combination.
✔ Those with moderate to severe acne seeking a clinically proven high-potency treatment
✔ Those with persistent breakouts, congestion, or post-acne marks
✔ Those looking to address active acne and post-inflammatory hyperpigmentation simultaneously
✔ Those who have not achieved sufficient results with lower-potency acne treatments
✔ Suitable under the guidance of a skincare provider as part of a supervised acne management programme
Retinol + Blemish Complex is specifically formulated for acne-prone skin, combining retinol with encapsulated salicylic acid and tranexamic acid to target all stages of acne formation and post-acne pigmentation. Retinol Skin Brightener is formulated primarily for uneven skin tone and brightening, using retinol alongside brightening actives. Your skincare provider will advise on the most appropriate retinol product for your skin concerns.
Combining multiple high-potency actives increases the risk of irritation and barrier disruption. Consult your skincare provider before using Retinol + Blemish Complex alongside other exfoliating or acne treatment products such as Oil Control Pads or Dual Action Scrub.
Initial improvement in skin clarity and blemish frequency is typically noticeable within 4–6 weeks of consistent use. More significant improvements in acne severity, skin texture, and post-acne marks develop over 3–6 months of continued use at full daily frequency.