ZO Skin Health® Aggressive Anti-Ageing Program

ZO Skin Health® Aggressive Anti-Ageing Program – A Complete High-Potency Regimen for Advanced Skin Renewal

A Comprehensive, Clinically Formulated Programme for Those Seeking Maximum Anti-Ageing Results

The ZO Skin Health® Aggressive Anti-Ageing Program is a curated, multi-step skincare regimen designed for patients with moderate to advanced signs of skin ageing who require a more intensive approach to skin renewal. Combining high-potency actives across cleansing, exfoliation, treatment, and protection, this programme delivers a systematic and evidence-based approach to visibly reducing fine lines and wrinkles, improving skin texture and tone, and supporting long-term skin health.

Formulated by Dr Zein Obagi, this programme represents the most intensive over-the-counter anti-ageing regimen within the ZO Skin Health® range and is recommended for use under the guidance of a skincare provider.

Recommended Regimen – Step by Step

Step 1 — Cleanse: Hydrating Cleanser

A gentle, hydrating cleanser for dry and sensitised skin. Use morning and evening as part of the Getting Skin Ready® routine.

Step 2 — Exfoliate: Exfoliating Polish

A best-selling exfoliator suitable for all skin types. Ultra-fine magnesium crystals smooth skin texture and promote healthy cell renewal. Use morning or evening.

Step 3 — Tone: Complexion Renewal Pads

Pre-moistened exfoliating pads for all skin types. Remove dead skin cells, minimise surface oil, and prepare the skin for active treatment products. Use morning and evening.

Step 4 — Prevent + Correct: Daily Power Defence

An advanced barrier serum that defends against environmental stressors and premature signs of ageing. Suitable for all skin types. Use morning and evening.

Step 5 — Prevent + Correct: Renewal Crème

A lightweight hydrator clinically proven to revitalise the appearance of stressed skin. Suitable for dry to sensitised skin. Use morning or evening.

Step 6 — Prevent + Correct: Radical Night Retinol

Formulated with 1% retinol to improve skin texture and uneven pigmentation. Suitable for all skin types. Use in the evening only.

Key Benefits

• Targets Advanced Signs of Ageing
  High-potency actives including retinol and antioxidant complexes work together to visibly reduce fine lines, wrinkles, and skin laxity.
• Accelerates Skin Renewal
  Multi-step exfoliation and retinol treatment promote faster cellular turnover, revealing fresher, smoother skin.
• Protects and Repairs
  DNA repair enzyme technology and antioxidant protection defend against ongoing environmental damage while supporting the skin’s natural recovery.
• Improves Skin Texture and Tone
  Consistent use delivers a progressively smoother, more even complexion with improved clarity and radiance.
• Systematic, Evidence-Based Approach
  Each product in the programme is formulated to work synergistically, maximising the efficacy of the overall regimen.

Programme Details

• Price: £235
• Suitable for: Moderate to advanced signs of ageing; experienced skincare users
• Use: Under the guidance of a skincare provider
• Intensity: High-potency — the most intensive OTC anti-ageing programme in the ZO Skin Health® range

Who Should Use This

✔ Those with moderate to advanced signs of skin ageing seeking a comprehensive, high-potency regimen
✔ Experienced skincare users comfortable with retinol and active ingredients
✔ Patients under the guidance of a skincare provider as part of a supervised anti-ageing programme
✔ Those looking to maximise the results of their at-home skincare with a complete, systematically designed regimen

Safety Information

• Daily SPF is Essential: This programme contains retinol and AHAs, both of which increase photosensitivity. Broad-spectrum SPF 30+ must be used every morning.
• Pregnancy and Breastfeeding: This programme contains retinol, which is contraindicated during pregnancy and breastfeeding. Do not use.
• Not Suitable for Retinol Beginners: The Radical Night Retinol included in this programme is a high-potency retinol formulation. Those new to retinol should begin with a lower-strength product under guidance.
• Discontinue if Severe Irritation Occurs: Consult your skincare provider if significant redness, peeling, or discomfort develops.
• For External Use Only.

Frequently Asked Questions

How does this differ from the ZO Skin Health® Anti-Ageing Program?

The Aggressive Anti-Ageing Program includes Radical Night Retinol at 1% concentration, making it the more intensive of the two programmes. The Anti-Ageing Program is formulated for those with earlier signs of ageing or those who require a more moderate introduction to active skincare. Your skincare provider will advise on the most appropriate programme for your skin.

Do I need a consultation before starting this programme?

Use under the guidance of a skincare provider is strongly recommended, particularly given the high-potency retinol content. A consultation will ensure the programme is appropriate for your skin type and that you receive a personalised introduction protocol.

Can I add additional ZO Skin Health® products to this programme?

Yes — your skincare provider may recommend additional products such as a targeted serum, eye treatment, or SPF to complement the programme based on your specific skin concerns.

How long before I see results?

Initial improvements in skin texture and radiance are typically noticeable within 4–6 weeks. More significant reductions in fine lines, wrinkles, and skin laxity develop over 3–6 months of consistent use.