







OBAGI NU-CIL® Eyelash Enhancing Serum is a clinically developed, medical-grade lash serum formulated to visibly increase eyelash length, density, and fullness. Powered by a proprietary peptide-rich complex and nourishing botanical actives, NU-CIL® works at the follicular level to extend the natural lash growth cycle — delivering measurably longer, thicker, and darker lashes without the hormonal side effects associated with prostaglandin-based alternatives.
Developed by OBAGI Medical — a brand trusted by dermatologists and aesthetic clinicians worldwide for over 35 years — NU-CIL® represents the gold standard in non-prescription lash enhancement.
Eyelash growth follows a cyclical pattern: the anagen phase (active growth), the catagen phase (transition), and the telogen phase (resting/shedding). Most people naturally spend only 30–45 days in the anagen phase — limiting how long lashes can grow.
NU-CIL® is formulated to extend the anagen phase and nourish the follicle during this window, resulting in lashes that grow longer before shedding. The formula combines:
Unlike prostaglandin analogues (found in prescription treatments such as bimatoprost), NU-CIL® achieves its results through follicular nourishment and peptide signalling — making it safe for long-term daily use without the systemic or ocular risks associated with prescription alternatives.
Prescription lash serums containing prostaglandin analogues (e.g. bimatoprost, isopropyl cloprostenate) can cause well-documented side effects including:
OBAGI NU-CIL® delivers clinically meaningful lash enhancement without any of these risks, making it the preferred choice for patients who want results without compromise — and the recommendation of choice among aesthetic clinicians for long-term maintenance.
Pro tip: Results are cumulative. Discontinuing use will gradually return lashes to their pre-treatment state as the natural growth cycle reasserts itself — consistent use is key.
NU-CIL® is suitable for adults who:
Not recommended for: use during pregnancy or breastfeeding without medical advice; individuals with active eye infections or inflammation; those under 18 years of age.
| Brand | OBAGI Medical |
|---|---|
| Product | NU-CIL® Eyelash Enhancing Serum |
| Size | 3 ml |
| Formula type | Prostaglandin-free peptide serum |
| Application | Precision brush applicator |
| Frequency | Once daily (evening recommended) |
| Visible results | 4–6 weeks; optimal at 12–16 weeks |
| Ophthalmologist tested | Yes |
| Contact lens safe | Yes (remove lenses before application) |
| Prescription required | No |
Most users notice initial improvements in lash length and fullness within 4–6 weeks of consistent daily use. Optimal, full results are typically achieved at 12–16 weeks. Results are cumulative and depend on consistent application — skipping applications will slow progress.
Yes. NU-CIL® is formulated to be contact lens-compatible. Remove contact lenses before applying the serum and wait at least 15 minutes before reinserting them.
No. OBAGI NU-CIL® is completely prostaglandin-free. It achieves lash enhancement through a peptide and botanical complex rather than prostaglandin analogues, eliminating the risk of iris colour change, periorbital fat loss, or increased intraocular pressure associated with prostaglandin-based serums.
Lashes will gradually return to their natural pre-treatment state as the growth cycle reasserts itself — typically over 4–8 weeks after discontinuation. To maintain results, continued use is recommended. Many users transition to every-other-day application as a maintenance dose once optimal results are achieved.
NU-CIL® is specifically formulated and tested for eyelash use. While some users apply it to sparse brow areas, this is an off-label use. Consult your skincare professional for brow-specific treatment recommendations.
Prescription lash serums (such as those containing bimatoprost) work via prostaglandin pathways and can produce dramatic results, but carry documented risks including iris pigmentation changes and periorbital fat atrophy. OBAGI NU-CIL® uses a peptide-based mechanism that is safer for long-term use, suitable without a prescription, and preferred by many clinicians for maintenance therapy or for patients who cannot tolerate prostaglandin side effects.
Use during pregnancy or breastfeeding is not recommended without prior medical advice. Please consult your GP or obstetrician before use if you are pregnant, planning a pregnancy, or breastfeeding.
OBAGI products are professional-grade formulations designed for use under clinical guidance. Purchasing from an authorised, clinician-backed retailer ensures you receive:
Counterfeit and grey-market OBAGI products are a known issue in the UK market. Always verify you are purchasing from an authorised OBAGI stockist.