{"product_id":"zo-skin-growth-factor-serum","title":"ZO Skin Health® Growth Factor Serum","description":"\u003cdiv class=\"product-description\"\u003e\n  \u003cp\u003e\u003cstrong\u003eZO Skin Health® Growth Factor Serum is an advanced age-management serum powered by five safely synthesised, human-comparable growth factors.\u003c\/strong\u003e The next-generation formula delivers targeted skin-signalling technology to improve the visible appearance of skin density, elasticity, firmness and smoothness.\u003c\/p\u003e\n\n  \u003cp\u003eDeveloped for skin showing moderate to advanced signs of ageing, this sophisticated 30ml serum supports a thicker, more supple and better-hydrated appearance while temporarily reducing the look of expression lines. In ZO Skin Health’s reported clinical assessment, skin appeared nearly six years younger on average after eight weeks of twice-daily use.\u003c\/p\u003e\n\n  \u003ch2\u003eNext-Generation ZO Growth Factor Technology\u003c\/h2\u003e\n\n  \u003cp\u003eGrowth factors are specialised signalling proteins involved in communication between cells. Within skincare, carefully formulated growth-factor technology is used to support the processes associated with healthier-looking, more resilient skin.\u003c\/p\u003e\n\n  \u003cp\u003eThe new generation of ZO Growth Factor Serum uses five safely synthesised growth factors designed to be comparable with signalling proteins naturally present in human skin. This allows the formulation to target several visible characteristics associated with skin ageing rather than addressing surface hydration alone.\u003c\/p\u003e\n\n  \u003cp\u003eThe five-factor system includes:\u003c\/p\u003e\n\n  \u003cul\u003e\n    \u003cli\u003e\n\u003cstrong\u003eEpidermal Growth Factor (EGF)\u003c\/strong\u003e — supports signalling associated with epidermal renewal and a smoother-looking skin surface.\u003c\/li\u003e\n    \u003cli\u003e\n\u003cstrong\u003eInsulin-Like Growth Factor 1 (IGF-1)\u003c\/strong\u003e — contributes to the formula’s support for skin density, resilience and visible vitality.\u003c\/li\u003e\n    \u003cli\u003e\n\u003cstrong\u003eAcidic Fibroblast Growth Factor (aFGF)\u003c\/strong\u003e — forms part of the signalling complex directed towards firmer and more supple-looking skin.\u003c\/li\u003e\n    \u003cli\u003e\n\u003cstrong\u003eBasic Fibroblast Growth Factor (bFGF)\u003c\/strong\u003e — complements the serum’s approach to visible skin thickness, elasticity and structural quality.\u003c\/li\u003e\n    \u003cli\u003e\n\u003cstrong\u003eVascular Endothelial Growth Factor (VEGF)\u003c\/strong\u003e — completes the five-factor technology supporting a healthier and more revitalised appearance.\u003c\/li\u003e\n  \u003c\/ul\u003e\n\n  \u003cp\u003eTogether, these human-comparable growth factors provide a coordinated signalling system developed to improve the visible qualities that commonly decline with age: thickness, elasticity, firmness, smoothness and suppleness.\u003c\/p\u003e\n\n  \u003ch2\u003eWhy Skin Density and Elasticity Matter\u003c\/h2\u003e\n\n  \u003cp\u003eAgeing skin can gradually appear thinner, less resilient and more visibly creased. Changes in its supporting structure, hydration and natural renewal processes may contribute to expression lines, uneven texture and a loss of firmness.\u003c\/p\u003e\n\n  \u003cp\u003eZO Growth Factor Serum is designed to address this broader pattern of visible ageing. Its objective is not simply to soften the surface temporarily, but to support skin that progressively appears denser, smoother, firmer and more elastic with consistent use.\u003c\/p\u003e\n\n  \u003cp\u003eThis makes it particularly relevant when the complexion has begun to look less substantial or when conventional hydration alone no longer provides the desired improvement in visible skin quality.\u003c\/p\u003e\n\n  \u003ch2\u003eClinically Assessed Age-Management Benefits\u003c\/h2\u003e\n\n  \u003cp\u003eZO Skin Health evaluated the next-generation Growth Factor Serum in an independent, third-party clinical study involving 46 women aged 44 to 74. Participants had moderate to severe visible signs of ageing and represented Fitzpatrick skin types II to VI.\u003c\/p\u003e\n\n  \u003cp\u003eThe serum was used twice daily for 12 weeks alongside Gentle Cleanser and Sheer Fluid Broad-Spectrum Sunscreen SPF 50. ZO reports that after eight weeks:\u003c\/p\u003e\n\n  \u003cul\u003e\n    \u003cli\u003eSkin showed visible improvement in thickness and elasticity\u003c\/li\u003e\n    \u003cli\u003eSkin appeared smoother and more supple\u003c\/li\u003e\n    \u003cli\u003eHydration and visible firmness improved\u003c\/li\u003e\n    \u003cli\u003eExpression lines appeared temporarily reduced\u003c\/li\u003e\n    \u003cli\u003eSkin appeared nearly six years younger on average according to subject assessments\u003c\/li\u003e\n  \u003c\/ul\u003e\n\n  \u003cp\u003eThe “six years younger” figure is based on the average assessment recorded within the study rather than a guaranteed result for every individual. Continued and consistent use within a professionally selected skincare programme is important.\u003c\/p\u003e\n\n  \u003ch2\u003eKey Benefits of ZO Growth Factor Serum\u003c\/h2\u003e\n\n  \u003cul\u003e\n    \u003cli\u003ePowered by five safely synthesised, human-comparable growth factors\u003c\/li\u003e\n    \u003cli\u003eImproves the visible appearance of skin thickness and density\u003c\/li\u003e\n    \u003cli\u003eSupports firmer and more elastic-looking skin\u003c\/li\u003e\n    \u003cli\u003ePromotes a smoother and more refined skin surface\u003c\/li\u003e\n    \u003cli\u003eRestores the look of suppleness and visible vitality\u003c\/li\u003e\n    \u003cli\u003eProvides supportive hydration\u003c\/li\u003e\n    \u003cli\u003eTemporarily reduces the appearance of expression lines\u003c\/li\u003e\n    \u003cli\u003eAddresses multiple visible signs of ageing simultaneously\u003c\/li\u003e\n    \u003cli\u003eSuitable for all skin types\u003c\/li\u003e\n    \u003cli\u003eNon-comedogenic\u003c\/li\u003e\n    \u003cli\u003eClinically tested\u003c\/li\u003e\n    \u003cli\u003eFormulated without parabens or gluten\u003c\/li\u003e\n  \u003c\/ul\u003e\n\n  \u003ch2\u003eWho Is ZO Growth Factor Serum For?\u003c\/h2\u003e\n\n  \u003cp\u003eZO Growth Factor Serum is suitable for all skin types and may be particularly relevant for people concerned about:\u003c\/p\u003e\n\n  \u003cul\u003e\n    \u003cli\u003eVisible loss of skin firmness\u003c\/li\u003e\n    \u003cli\u003eReduced elasticity or resilience\u003c\/li\u003e\n    \u003cli\u003eThin or fragile-looking skin\u003c\/li\u003e\n    \u003cli\u003eExpression lines and visible creasing\u003c\/li\u003e\n    \u003cli\u003eUneven or rough-looking texture\u003c\/li\u003e\n    \u003cli\u003eLoss of suppleness\u003c\/li\u003e\n    \u003cli\u003eDehydrated or less vibrant-looking skin\u003c\/li\u003e\n    \u003cli\u003eModerate to advanced visible signs of ageing\u003c\/li\u003e\n    \u003cli\u003eMaintaining skin quality within a comprehensive ZO programme\u003c\/li\u003e\n  \u003c\/ul\u003e\n\n  \u003cp\u003eIts multi-pathway approach makes it especially valuable where several signs of ageing are present together. A Skin By Science consultation helps establish its role alongside the other active products within an individual ZO protocol.\u003c\/p\u003e\n\n  \u003ch2\u003eTexture and Finish\u003c\/h2\u003e\n\n  \u003cp\u003eGrowth Factor Serum has a refined gel-serum texture designed to distribute evenly across clean, dry skin. It provides hydration without behaving like a conventional heavy moisturiser and can be incorporated into both morning and evening programmes.\u003c\/p\u003e\n\n  \u003cp\u003eIts finish allows subsequent skincare and daytime sun protection to be layered according to the sequence selected for the individual.\u003c\/p\u003e\n\n  \u003ch2\u003eDirections\u003c\/h2\u003e\n\n  \u003col\u003e\n    \u003cli\u003eApply to clean, dry skin.\u003c\/li\u003e\n    \u003cli\u003eDistribute the serum evenly across the face and other areas included within the personalised programme.\u003c\/li\u003e\n    \u003cli\u003eUse morning and evening unless an alternative frequency has been recommended.\u003c\/li\u003e\n    \u003cli\u003eFollow with the remaining Prevent + Correct products selected for the ZO protocol.\u003c\/li\u003e\n    \u003cli\u003eComplete the morning programme with appropriate broad-spectrum sunscreen.\u003c\/li\u003e\n  \u003c\/ol\u003e\n\n  \u003cp\u003eWhen Growth Factor Serum is being combined with retinol, exfoliating treatments or other high-activity ZO formulations, follow the product sequence and frequency established during consultation.\u003c\/p\u003e\n\n  \u003ch2\u003eIts Role Within a ZO Skin Health Programme\u003c\/h2\u003e\n\n  \u003cp\u003eZO Growth Factor Serum occupies a targeted age-management position within the Prevent + Correct stage of a ZO programme. It concentrates on visible density, elasticity, firmness, smoothness and expression lines through advanced growth-factor signalling technology.\u003c\/p\u003e\n\n  \u003cp\u003e\u003ca href=\"\/products\/zo-skin-daily-power-defence\"\u003eZO Skin Health Daily Power Defence\u003c\/a\u003e may provide complementary daily support for hydration, barrier resilience and environmental defence across the face. The two products have distinct roles and can be positioned together when appropriate within a professionally selected programme.\u003c\/p\u003e\n\n  \u003cp\u003eDaily broad-spectrum sun protection remains essential when addressing visible ageing. \u003ca href=\"\/products\/zo-skin-health%C2%AE-sheer-fluid-broad-spectrum-spf-50\"\u003eZO Skin Health Sheer Fluid Broad-Spectrum SPF 50\u003c\/a\u003e can provide the final protective step where it has been selected for the individual’s routine.\u003c\/p\u003e\n\n  \u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\n  \u003ch3\u003eWhat does ZO Growth Factor Serum do?\u003c\/h3\u003e\n\n  \u003cp\u003eIt is designed to improve the appearance of skin thickness, density, elasticity, firmness and smoothness. It also supports hydration, restores a more supple appearance and temporarily reduces the look of expression lines.\u003c\/p\u003e\n\n  \u003ch3\u003eWhat makes this the next-generation formula?\u003c\/h3\u003e\n\n  \u003cp\u003eThe current formula is powered by five safely synthesised, human-comparable growth factors. This replaces the older generation of Growth Factor Serum that was commonly described using plant-derived growth factors and ZPRO® technology.\u003c\/p\u003e\n\n  \u003ch3\u003eWhich growth factors does it contain?\u003c\/h3\u003e\n\n  \u003cp\u003eZO’s human-comparable growth-factor technology incorporates EGF, IGF-1, acidic FGF, basic FGF and VEGF. Together, they form a coordinated signalling complex developed to support younger-looking skin.\u003c\/p\u003e\n\n  \u003ch3\u003eWhat does “human-comparable” mean?\u003c\/h3\u003e\n\n  \u003cp\u003eIt means the growth factors are safely synthesised to be comparable with naturally occurring human signalling proteins. The description does not mean that the ingredients are taken directly from human skin.\u003c\/p\u003e\n\n  \u003ch3\u003eDoes Growth Factor Serum contain human-derived material?\u003c\/h3\u003e\n\n  \u003cp\u003eZO describes the five growth factors as safely synthesised and human-comparable. They are used to deliver targeted signalling within the cosmetic formulation.\u003c\/p\u003e\n\n  \u003ch3\u003eHow quickly can visible results appear?\u003c\/h3\u003e\n\n  \u003cp\u003eZO reports clinically assessed improvements after eight weeks of twice-daily use. The supporting study continued for 12 weeks, and individual results can vary according to skin condition, consistency and the wider programme.\u003c\/p\u003e\n\n  \u003ch3\u003eCan it really make skin look six years younger?\u003c\/h3\u003e\n\n  \u003cp\u003eZO reports that participants’ skin appeared nearly six years younger on average after eight weeks, based on subject assessments in its clinical study. This is an average study outcome rather than a guaranteed result for every user.\u003c\/p\u003e\n\n  \u003ch3\u003eIs it suitable for all skin types?\u003c\/h3\u003e\n\n  \u003cp\u003eYes. ZO identifies Growth Factor Serum as suitable for all skin types. Consultation remains valuable because the wider programme should reflect individual skin condition, sensitivity and treatment objectives.\u003c\/p\u003e\n\n  \u003ch3\u003eIs it non-comedogenic?\u003c\/h3\u003e\n\n  \u003cp\u003eYes. The current formulation is identified by ZO as non-comedogenic.\u003c\/p\u003e\n\n  \u003ch3\u003eCan Growth Factor Serum be used morning and evening?\u003c\/h3\u003e\n\n  \u003cp\u003eYes. ZO directs the serum to be applied to clean, dry skin in the morning and evening as part of the selected Prevent + Correct programme.\u003c\/p\u003e\n\n  \u003ch3\u003eCan it be combined with ZO retinol?\u003c\/h3\u003e\n\n  \u003cp\u003eGrowth Factor Serum can form part of a programme that also contains a ZO retinol. The strength, frequency and sequence of high-activity products should be selected around the individual’s skin tolerance and objectives.\u003c\/p\u003e\n\n  \u003ch3\u003eDoes it replace moisturiser?\u003c\/h3\u003e\n\n  \u003cp\u003eIt provides hydration, but its principal purpose is advanced growth-factor-led age management. Whether an additional hydration or barrier-supporting product is required depends on skin condition and the structure of the wider programme.\u003c\/p\u003e\n\n  \u003ch3\u003eDoes it replace sunscreen?\u003c\/h3\u003e\n\n  \u003cp\u003eNo. Growth Factor Serum is a corrective age-management serum. Appropriate broad-spectrum sunscreen should be applied as the final stage of the morning skincare programme.\u003c\/p\u003e\n\n  \u003ch3\u003eWhy is consultation required?\u003c\/h3\u003e\n\n  \u003cp\u003eSkin By Science supplies ZO Skin Health following consultation so that Growth Factor Serum can be positioned correctly alongside other active products and selected according to the individual’s skin condition, tolerance and objectives.\u003c\/p\u003e\n\n  \u003ch2\u003eProduct Details\u003c\/h2\u003e\n\n  \u003cul\u003e\n    \u003cli\u003e\n\u003cstrong\u003eProduct:\u003c\/strong\u003e ZO Skin Health® Growth Factor Serum\u003c\/li\u003e\n    \u003cli\u003e\n\u003cstrong\u003eSize:\u003c\/strong\u003e 30ml\u003c\/li\u003e\n    \u003cli\u003e\n\u003cstrong\u003eFormat:\u003c\/strong\u003e Advanced gel face serum\u003c\/li\u003e\n    \u003cli\u003e\n\u003cstrong\u003eTechnology:\u003c\/strong\u003e Five safely synthesised, human-comparable growth factors\u003c\/li\u003e\n    \u003cli\u003e\n\u003cstrong\u003eGrowth factors:\u003c\/strong\u003e EGF, IGF-1, acidic FGF, basic FGF and VEGF\u003c\/li\u003e\n    \u003cli\u003e\n\u003cstrong\u003ePrincipal concerns:\u003c\/strong\u003e Visible loss of density, elasticity, firmness, smoothness and suppleness\u003c\/li\u003e\n    \u003cli\u003e\n\u003cstrong\u003eSkin types:\u003c\/strong\u003e All skin types\u003c\/li\u003e\n    \u003cli\u003e\n\u003cstrong\u003eRecommended use:\u003c\/strong\u003e Morning and evening\u003c\/li\u003e\n    \u003cli\u003e\n\u003cstrong\u003eTesting:\u003c\/strong\u003e Clinically tested and non-comedogenic\u003c\/li\u003e\n    \u003cli\u003e\n\u003cstrong\u003eFormulation:\u003c\/strong\u003e Paraben free and formulated without gluten\u003c\/li\u003e\n    \u003cli\u003e\n\u003cstrong\u003eSupply:\u003c\/strong\u003e Following Skin By Science consultation\u003c\/li\u003e\n  \u003c\/ul\u003e\n\n  \u003cp\u003e\u003cstrong\u003eIngredient information:\u003c\/strong\u003e Refer to the packaging supplied with the product for the current complete ingredient declaration, particularly when checking known allergies or sensitivities.\u003c\/p\u003e\n\n  \u003cp\u003e\u003cem\u003eClinical-study information and reported results are supplied by ZO Skin Health. The study involved 46 female subjects aged 44–74 with Fitzpatrick skin types II–VI and moderate to severe visible signs of ageing. Individual results can vary.\u003c\/em\u003e\u003c\/p\u003e\n\n  \u003cdetails style=\"margin-top: 28px; border-top: 1px solid #dedede; border-bottom: 1px solid #dedede; padding: 14px 0;\"\u003e\n    \u003csummary style=\"cursor: pointer; font-weight: 600;\"\u003eExplore related ZO Skin Health information\u003c\/summary\u003e\n\n    \u003cdiv style=\"padding-top: 12px;\"\u003e\n      \u003cp style=\"margin: 0 0 12px;\"\u003e\n        \u003ca href=\"\/pages\/free-consultation\"\u003eFree skin consultation for your ZO programme\u003c\/a\u003e\n      \u003c\/p\u003e\n\n      \u003cp style=\"margin: 0;\"\u003e\n        \u003ca href=\"\/blogs\/news\/what-is-zo-skin-health-brand-guide\"\u003eZO Skin Health: professional skincare and programme guide\u003c\/a\u003e\n      \u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/details\u003e\n\u003c\/div\u003e","brand":"ZO Skin Health®","offers":[{"title":"Default Title","offer_id":50607700672859,"sku":"18","price":125.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0916\/9338\/4027\/files\/zo-growth-factor-serum-30ml.avif?v=1789238295","url":"https:\/\/skinbyscience.co.uk\/products\/zo-skin-growth-factor-serum","provider":"skinbyscience","version":"1.0","type":"link"}