Obagi Retinol 0.5 28g airless pump
Obagi Retinol 0.5 cream
Obagi Retinol 0.5 new pack
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Obagi Medical

OBAGI - Retinol 0.5

£80.00

Free UK delivery · 2–4 working days

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Product details

About OBAGI - Retinol 0.5

In short: A 0.5% retinol cream from Obagi that releases retinol gradually to smooth fine lines, wrinkles and rough texture with minimal irritation. It is the middle strength between Retinol + PHA (0.3%) and Retinol 1.0.

Obagi Retinol 0.5 28g

Obagi Retinol 0.5 is a cream-based 0.5% retinol for evening use. It renews the skin and gradually releases its actives to reduce the look of fine lines and wrinkles and promote skin turnover, with minimal irritation. Calendula, green tea, chamomile, bisabolol and hyaluronic acid help keep skin comfortable.

It is a good next step once your skin is used to Retinol + PHA, before moving to Retinol 1.0. Retinol is a cosmetic retinoid, not prescription tretinoin. Genuine Obagi Medical stock from Obagi’s UK distribution.

Key benefits

  • Helps resurface skin and reduce the look of fine lines and wrinkles
  • Promotes skin turnover for smoother texture and more even tone
  • Gradual release for minimal irritation
  • Soothing botanicals and hyaluronic acid in a cream base

Key ingredients

  • Retinol 0.5%: vitamin A that smooths texture and reduces the look of lines and uneven tone
  • Calendula, green tea and chamomile extracts, bisabolol: soothing botanicals
  • Sodium hyaluronate and shea butter: hydration and comfort
  • Vitamins C and E: antioxidants

Full ingredients (Obagi Medical, obagi.com): water (aqua), caprylic/capric triglyceride, glyceryl stearate, cyclopentasiloxane, butylene glycol, stearic acid, polysorbate 60, butyrospermum parkii (shea) butter, glycerin, stearyl alcohol, cyclohexasiloxane, dimethicone, retinol, calendula officinalis flower extract, camellia sinensis leaf extract, chamomilla recutita (matricaria) flower extract, dipotassium glycyrrhizate, sodium hyaluronate, tocopheryl acetate, bisabolol, ascorbic acid, carthamus tinctorius (safflower) seed oil, sorbitol, glyceryl acrylate/acrylic acid copolymer, dimethicone/vinyl dimethicone crosspolymer, allyl methacrylates crosspolymer, caprylyl glycol, ethylhexylglycerin, hexylene glycol, polysorbate 20, carbomer, disodium EDTA, triethanolamine, BHT, phenoxyethanol. Always check the pack you receive, as formulations can change.

Who is it for?

  • Fine lines, wrinkles and rough or uneven texture
  • People who have used a lower-strength retinol and want to step up
  • Not for use in pregnancy or while breastfeeding. Ask your doctor or pharmacist if unsure

How to use

  1. Use once daily in the evening on clean, dry skin.
  2. Apply one pump, or a pearl-sized amount, to the face and massage in.
  3. If you get redness or peeling, use it every other night until your skin adjusts.
  4. Use SPF 30 or higher every morning.

Product details

  • Brand: Obagi Medical
  • Size: 28g
  • Retinol strength: 0.5%
  • Format: Airless pump cream
  • Use: Evening

Frequently asked questions

Which Obagi retinol should I start with?

New to retinol: Retinol + PHA (0.3%). Some experience: Retinol 0.5. Experienced users: Retinol 1.0.

Is mild peeling normal?

Mild redness, peeling or irritation can happen as skin adjusts. Obagi suggests every-other-night use until it settles.

Can I use it with vitamin C?

Yes. Use vitamin C in the morning and retinol at night.

Do I need a prescription or consultation?

No. This is a cosmetic Obagi product, so you can add it to your basket and check out as normal.

Sources

Reviewed 10 November 2026 by Skin by Science against Obagi Medical product information. Cosmetic product, not a medicine. No prescription or consultation needed.