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In short: Obagi’s barrier-repair cream with BarrierPlex™ technology: postbiotics, ceramides, niacinamide and green algae. It soothes and rehydrates skin that is dry, sensitised, or recovering from treatments or strong actives such as tretinoin.
Rebalance is the cream Obagi made for skin that needs to recover. Its BarrierPlex™ technology blends postbiotics, hydrating agents and soothing ingredients to help restore the skin barrier and rebalance the skin’s microbiome. It has the National Eczema Association Seal of Acceptance (US).
It is a natural partner to strong routines such as tretinoin, Nu-Derm or chemical peels, and to skin that feels tight or reactive. Genuine Obagi Medical stock from Obagi’s UK distribution.
2022 bio-instrumentation study and 2022 4-week post-procedure study. Data on file at Obagi Cosmeceuticals LLC.
Full ingredients (Obagi Medical, obagi.com): Aqua/water/eau, caprylic/capric triglyceride, glycerin, cetearyl alcohol, squalane, glycol palmitate, coconut alkanes, niacinamide, hexyldecanol, cetearyl olivate, sorbitan olivate, maltodextrin, hydrogenated lecithin, ceramide NP, ceramide AP, ceramide EOP, phytosphingosine, hydrolyzed caesalpinia spinosa gum, caesalpinia spinosa gum, cetylhydroxyproline palmitamide, hydroxyphenyl propamidobenzoic acid, tetraselmis suecica extract, lactobacillus ferment, brassica campestris (rapeseed) sterols, punica granatum pericarp extract, bisabolol, arginine, allantoin, tocopherol, cholesterol, avena sativa (oat) kernel flour, coco-caprylate/caprate, pentylene glycol, butylene glycol, sodium lauroyl lactylate, stearic acid, acacia senegal gum, xanthan gum, carbomer, phenoxyethanol, caprylyl glycol, ethylhexylglycerin, disodium EDTA, citric acid. Always check the pack you receive, as formulations can change.
Yes. It is often used to comfort skin during tretinoin or Nu-Derm treatment. Follow your prescriber’s instructions for the prescription product.
Obagi tested it after procedures. If you had an ablative procedure, use it as your doctor directs.
No. This is a cosmetic Obagi product, so you can add it to your basket and check out as normal.
Reviewed 10 November 2026 by Skin by Science against Obagi Medical product information. Cosmetic product, not a medicine. No prescription or consultation needed.