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In short: The hydroquinone-free evening brightening cream from the Obagi Nu-Derm Fx system. It combines arbutin with vitamins C and E and gentle exfoliating acids to help clarify and even out the look of skin tone. No prescription needed.
Nu-Derm Blend Fx is the evening brightening cream of Obagi’s non-prescription Nu-Derm Fx system. In place of hydroquinone it uses arbutin, a nature-identical brightening agent, with antioxidants and an exfoliant to help clarify the skin and reduce the look of uneven tone.
It is a good fit if you want a hydroquinone-free option for dark spots and uneven tone, or if you are taking a break from a prescription pigmentation routine. It is not the same product as prescription Nu-Derm Blender, which contains hydroquinone. Genuine Obagi Medical stock from Obagi’s UK distribution.
Full ingredients (Obagi Medical, obagi.com): Aqua/water/eau, glycerin, cetyl alcohol, arbutin, PPG-2 myristyl ether propionate, sodium lauryl sulfate, TEA-salicylate, tocopheryl acetate, ascorbic acid, lactic acid, phenyl trimethicone, sodium metabisulfite, BHT, saponins, disodium EDTA, methylparaben, propylparaben. Always check the pack you receive, as formulations can change.
No. It uses arbutin. The prescription Nu-Derm Blender contains hydroquinone and is a different product.
Yes. In the Nu-Derm Fx system, Clear Fx is used morning and evening and Blend Fx in the evening.
It contains an alpha hydroxy acid, which can make skin more sensitive to the sun. Daily SPF also helps prevent new pigmentation.
No. This is a cosmetic Obagi product, so you can add it to your basket and check out as normal.
Reviewed 10 November 2026 by Skin by Science against Obagi Medical product information. Cosmetic product, not a medicine. No prescription or consultation needed.