

Skin ageing, inflammation, and cellular dysfunction don't begin at the surface — they begin at the level of individual cells. As skin cells lose their ability to communicate effectively, the cascade of decline accelerates: collagen synthesis slows, inflammation becomes chronic, and the skin's capacity for self-repair diminishes. Conventional topical ingredients address the symptoms. EXO|E D|TOX addresses the cause.
D|TOX by EXO|E is a daily exosome serum formulated from organic plant stem cell-derived exosomes — extracellular nano-particles that operate at a cellular level, delivering biological instructions that trigger regeneration, reduce inflammation, and restore optimal skin function. With 4 billion exosomes per 30ml and two decades of scientific development behind it, D|TOX represents a new category of medical-grade skincare: not surface treatment, but cellular communication.
Exosomes are tiny membrane-bound vesicles naturally secreted by cells as part of the body's intercellular communication system. Laden with mRNA, miRNA, proteins, and lipids, they bind to receptors on target cells and deliver precise biological instructions — influencing gene expression, cellular repair, inflammation regulation, and tissue regeneration.
In the context of skin biology, exosomes derived from plant stem cells have been shown to mimic the regenerative signalling of their parent cells — stimulating fibroblast activity, modulating inflammatory pathways, and supporting the skin's extracellular matrix. Unlike peptides or growth factors, which target individual pathways, exosomes operate as multi-signal biological messengers, triggering a coordinated regenerative response across multiple cellular mechanisms simultaneously.
EXO|E's formulations have been developed over two decades of scientific research, with D|TOX delivering clinically validated results across inflammation reduction, collagen stimulation, elastin production, and hyaluronic acid secretion.
Extracellular nano-particles derived from organic plant stem cells, carrying mRNA, miRNA, proteins, and lipids that communicate directly with skin cells. They reduce inflammation, stimulate collagen and elastin synthesis, and restore normal skin cell function — operating across multiple biological pathways simultaneously rather than targeting a single mechanism.
Phospholipid vesicles that encapsulate and protect active ingredients, significantly enhancing their penetration through the skin barrier and delivery to target cells. Liposomal encapsulation ensures that exosomes and co-actives reach the dermal layer where cellular communication occurs.
A supporting complex of bioactive small molecules that complement exosome activity, supporting the skin's regenerative processes and enhancing the overall biological response to treatment.
Size: 30ml
Exosome concentration: 4 billion per 30ml
Application: Twice daily (morning and evening)
Origin: Organic plant stem cell-derived
Suitable for all skin types
Can be used alongside other EXO|E products. For a personalised protocol, consult one of our skincare specialists at Skin by Science.
Exosomes are extracellular nano-particles naturally secreted by cells as part of the body's intercellular communication system. In skincare, plant stem cell-derived exosomes deliver biological instructions — carried in mRNA, miRNA, proteins, and lipids — directly to skin cells, triggering regeneration, reducing inflammation, and restoring cellular function. Unlike conventional actives that target single pathways, exosomes act as multi-signal messengers, coordinating a broad regenerative response across multiple cellular mechanisms simultaneously.
Exosome concentration and origin matter significantly. D|TOX delivers 4 billion plant stem cell-derived exosomes per 30ml — one of the highest concentrations available in a topical formulation — backed by two decades of scientific development. Many products that reference exosomes contain trace quantities insufficient to drive meaningful cellular signalling. EXO|E's formulations are built around exosome concentration as the primary active, not a marketing footnote.
D|TOX is clinically formulated to address ageing (collagen and elastin loss, fine lines, loss of firmness), acne, hyperpigmentation, and skin irritation. Its primary mechanism — reducing inflammation by 61% per application — makes it particularly effective for reactive, sensitised, or chronically inflamed skin, while its collagen and elastin stimulation delivers structural renewal for ageing concerns.
Most users notice improvements in skin texture, hydration, and inflammation within 2–4 weeks of consistent daily use. More significant improvements in firmness, fine lines, and pigmentation are typically visible at 6–8 weeks. Results compound with continued use as cellular communication and regenerative capacity are progressively restored.
Yes. D|TOX is suitable for all skin types, including sensitive and reactive skin. Its primary action is anti-inflammatory — reducing skin inflammation by 61% per application — making it particularly well-tolerated by compromised or irritated skin.
D|TOX is a detoxifying and regenerative exosome serum that reduces inflammation, stimulates the skin's own hyaluronic acid production, and boosts collagen and elastin — making it ideal as a daily regenerative treatment. RE|PAIR is a recovery-focused exosome serum with an enhanced growth factor and anti-inflammatory complex, designed to accelerate healing and amplify skin renewal. Both can be used as part of a daily routine, or together as the complete EXO|E protocol.
Yes. D|TOX is compatible with other skincare actives including retinoids, vitamin C, and AHAs. For a personalised protocol — particularly if using prescription-strength actives — consult one of our skincare specialists at Skin by Science.
Skin by Science is an authorised UK stockist of EXO|E. All products are sourced directly through official channels, ensuring authenticity, correct storage conditions, and full product integrity. Purchasing from unauthorised retailers risks receiving improperly stored or counterfeit products that may be ineffective or unsafe.
Product formulations may be updated from time to time. For accurate ingredient information, refer to your product packaging. For personalised skincare advice or to build a complete EXO|E protocol tailored to your skin concerns, consult one of our skincare specialists at Skin by Science.